PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

541 articles indexed across 24 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 36 from 1 topic.Sort: Newest | Oldest
Tenecteplase Shortens Stroke Treatment and Transfer Times
🔓 Free Teaser Analysis Neurology / Neuropharmacology Confirmatory Grade: Low

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

DAPT Shows Promise in Specific Minor Stroke Cases
Analysis Neurology / Neuropharmacology

Could DAPT be superior to alteplase for certain minor strokes?

Bleeding May Outpace Ischemic Recurrence in Young Stroke Survivors
Analysis Anticoagulation / Hematology Hypothesis-generating Grade: Low
Also in Neurology / Neuropharmacology

Young stroke survivors face significant bleeding risk on antithrombotic therapy.

RESTART tICrH: Randomized Test of 1- vs 4-Week DOAC Resumption
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Very Low
Also in Anticoagulation / Hematology

When should DOACs restart after brain bleeding? This trial aims to find out.

PRUs Track CYP2C19 Genotype but Not Stroke Recurrence
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Low

PRUs may identify clopidogrel resistance in stroke patients without genotyping.

AAN and AHS Release Updated Adult Migraine Prevention Pharmacotherapy Guideline
★ Editor's Pick Guideline Neurology / Neuropharmacology Practice-changing Grade: Moderate

New guidelines optimize migraine prevention with personalized strategies.

Rethinking Rigid DOAC Exclusion Rules for Stroke Thrombolysis
★ Editor's Pick Analysis Anticoagulation / Hematology Hypothesis-generating Grade: Very Low
Also in Neurology / Neuropharmacology

Reassessing IVT in recent DOAC exposure for stroke care.

Breakthrough Stroke on Anticoagulation: Identifiable Causes Double Recurrence Risk
Analysis Anticoagulation / Hematology Hypothesis-generating Grade: Low
Also in Neurology / Neuropharmacology

Ischemic strokes occur even with anticoagulation; drug interactions may be key.

NOACs Beat Warfarin on Cognition and Outcomes in AF Plus Alzheimer's
Analysis Anticoagulation / Hematology Confirmatory Grade: Low
Also in Neurology / Neuropharmacology

NOACs slow cognitive decline in AF with Alzheimer's disease.

Marine-Derived Drugs in Alzheimer's: Modest, Inconsistent Cognitive Signals
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Low

Marine-derived drugs show potential but varied cognitive effects in Alzheimer's.

Perampanel and levetiracetam both control SeLECTS with minor sleep differences
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Very Low

PER may enhance sleep in children with SeLECTS.

Real-world lecanemab in Chinese patients: low ARIA, financial-driven discontinuation
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Low

Lecanemab shows safety but no cognitive boost in real-world AD study.

Extension Data Bolster Case Against Amyloid Therapy Coverage Restrictions
Analysis Neurology / Neuropharmacology Confirmatory Grade: Low

Amyloid therapies show promise in Alzheimer's treatment.

THC:CBD Extract Modestly Eases Subjective MS Spasticity
Analysis Neurology / Neuropharmacology Confirmatory Grade: Low

Antidiabetic drug safety profiles expand significantly post-marketing.

Cladribine tablets sustain remission through two treatment-free years
Analysis Neurology / Neuropharmacology Confirmatory Grade: Low
Also in Ambulatory Care / MTM

Cladribine tablets show promise for sustained treatment-free remission in RMS.