PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

309 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing all 309 articles.Sort: Newest | Oldest
2026 Dyslipidemia Guideline: Target-Driven Therapy and the End of the Nonstatin Stepladder
🔓 Free Teaser Reference Card Cardiology / Anticoagulation

How the 2026 ACC/AHA guideline changes lipid clinic workflows with absolute LDL-C targets, non-sequential nonstatin selection, and universal Lp(a) testing.

Deprescribing: The Highest-Impact Clinical Service Pharmacists Can Deliver
🔓 Free Teaser Reference Card Geriatrics

Evidence-based frameworks for pharmacist-led deprescribing of PPIs, benzodiazepines, opioids, anticholinergics, and antihyperglycemics.

Shorter Courses + Optimized PK/PD: The Modern Stewardship Equation
🔓 Free Teaser Reference Card Infectious Disease / Antimicrobials

Evidence-based guidance on antibiotic duration and beta-lactam infusion optimization for practicing pharmacists.

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD
🔓 Free Teaser Analysis Nephrology / Renal Pharmacy Confirmatory Grade: Moderate

Finerenone emerges as the safer choice for CKD patients.

Tenecteplase Shortens Stroke Treatment and Transfer Times
🔓 Free Teaser Analysis Neurology / Neuropharmacology Confirmatory Grade: Low

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations
🔓 Free Teaser Guideline Rheumatology / Immunology Confirmatory Grade: Moderate

New EULAR guidelines redefine RA management with DMARDs.

2026 ACC/AHA/Multisociety Dyslipidemia Guideline Reframes Lipid Management and Targets
🔓 Free Teaser Guideline Dyslipidemia Practice-changing Grade: Moderate

The 2026 ACC/AHA/Multisociety guideline introduces lower treatment goals, formal risk equations, and mandates Lp(a) assessment for dyslipidemia pharmacists.

2026 ADA Standards of Care in Diabetes Update
🔓 Free Teaser Guideline Diabetes Practice-changing Grade: Moderate

Introduces expanded diabetes screening and diagnostic recommendations across diverse populations for pharmacy practice.

2025 AHA/ACC Multi-Society Hypertension Guideline Redefines Risk and Treatment Thresholds
🔓 Free Teaser Guideline Hypertension Practice-changing Grade: Moderate

The 2025 AHA/ACC Guideline introduces PREVENT-based CVD risk, new secondary hypertension triggers, and major changes in initial drug therapy for pharmacists managing hypertension.

Dexmedetomidine vs Clonidine vs Propofol: Extubation in ICU Patients
🔓 Free Teaser Analysis Critical Care / ICU

The A2B trial evaluates sedation strategies on extubation timing in critical care.

2025 ACIP Adult Immunization Schedule Introduces Major Universal Vaccine Expansions
🔓 Free Teaser Guideline Immunization Practice-changing Grade: Moderate

The 2025 ACIP adult schedule features universal and risk-based expansions for pneumococcal, RSV, and polio vaccines, plus product, schedule, and note updates directly relevant to pharmacists.

In-Hospital Dapagliflozin Misses Primary Endpoint but Mortality Signal Persists
🔓 Free Teaser Analysis Cardiology / Anticoagulation Confirmatory Grade: Moderate

The largest, most rigorous trial of in-hospital sodium-glucose cotransporter-2 inhibitor initiation was formally neutral, but pooled trial data continue to support early inpatient start for hospitalized heart failure patients.

2023 ACC/AHA/ACCP/HRS AFib Guideline Overhauls Antithrombotic Management Framework
🔓 Free Teaser Guideline AFib/Antithrombotics Practice-changing Grade: Moderate

Major changes in stroke risk assessment, anticoagulant preferences, and DOAC over warfarin guidance will alter daily pharmacist management of AFib patients.

Key Changes in 2023 AGS Beers Criteria for Inappropriate Medications in Older Adults
🔓 Free Teaser Guideline Beers Criteria Practice-changing Grade: Moderate

The 2023 AGS Beers Criteria update introduces significant modifications and new recommendations impacting antihyperglycemics, anticoagulants, anticholinergics, and select drug–disease interactions for older adults.

GOLD 2023 COPD Report: Major Revisions from the Global Initiative for COPD
🔓 Free Teaser Guideline COPD Practice-changing Grade: Moderate

The GOLD 2026 update brings significant changes impacting risk stratification, exacerbation management, biologics, and vaccination in COPD care.