PharmD Signal

Deep dives, evidence grades, and clinical tools, all in one place.

🧠 Clinical library

Clinical Specialty Index

309 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

⭐ Featured free samples

Three of our best full deep-analysis reports: hand-picked, free to read in full, no subscription required.

🔓 Free Sample
Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

Read Free →
🔓 Free Sample
Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

Read Free →
🔓 Free Sample
Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

Read Free →
Showing 12 from 1 topic.Sort: Newest | Oldest
Short-Course Steroids Trigger HBV Reactivation in COVID-19
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Very Low

Screen for HBV before giving corticosteroids to COVID-19 patients.

Adding Camrelizumab to TACE Plus Donafenib in PVTT-Positive HCC
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low

Transarterial chemoembolization with donafenib and camrelizumab may extend survival in challenging liver cancer cases.

Rifaximin in Pediatric Hepatic Encephalopathy: First Trial, Ammonia Miss
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low

Rifaximin shows promise in pediatric hepatic encephalopathy treatment.

Ustekinumab Salvages Pediatric IBD After Anti-TNF Failure
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low

Could ustekinumab be the answer for pediatric IBD post-anti-TNF failure?

Fibrosis-Directed MASH Therapeutics Enter the Approved-Drug Era
Analysis Gastroenterology / Hepatology Confirmatory Grade: Low

MASLD leads global liver disease, now with targeted therapies emerging.

Mirikizumab sustains multidomain UC remission through four years
Analysis Gastroenterology / Hepatology Confirmatory Grade: Low

Four-year study shows lasting ulcerative colitis remission with mirikizumab.

AASLD Adds Semaglutide to MASH Practice Guidance With NIT-Based Selection
Guideline Gastroenterology / Hepatology Practice-changing Grade: Moderate

Semaglutide offers new hope for MASH management with significant fibrosis improvement.

Resmetirom Update: Positioning the First Approved MASH Therapy
Analysis Gastroenterology / Hepatology Confirmatory Grade: Moderate

Resmetirom is the first drug to reverse MASH and fibrosis.

Resmetirom Efficacy Holds With GLP-1 or SGLT2 Background; Weight Loss Amplifies It
Analysis Gastroenterology / Hepatology Confirmatory Grade: Moderate

Resmetirom shows promise in MASH, especially with weight loss.

EASL-EASD-EASO Guidelines Redefine MASLD Care With Resmetirom Entry
Guideline Gastroenterology / Hepatology Practice-changing Grade: Moderate

New guidelines transform MASLD management with non-invasive testing and targeted therapies.

Survodutide Improves MASH Histology Across Doses in Phase 2
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Moderate

Survodutide shows promise in treating MASH without worsening fibrosis.

Tirzepatide Resolves MASH but Fibrosis Benefit Remains Unproven
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Moderate

Tirzepatide offers potential new hope for MASH management.