PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

547 articles indexed across 24 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 38 from 1 topic.Sort: Newest | Oldest
Mirikizumab Sustains Four-Year Remission in Ulcerative Colitis Responders
Analysis Rheumatology / Immunology Confirmatory Grade: Low
Also in Gastroenterology / Hepatology

Provider training can drive HPV vaccine uptake in young adults.

Sofosbuvir/Velpatasvir Handles Novel Hepatitis C Subtypes; Genotype 3b Remains a Concern
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Also in Gastroenterology / Hepatology

SOF/VEL shows promise against diverse HCV genotypes, including novel subtypes.

Second-Line HCC After TKI Failure: Efficacy Versus Toxicity Network Analysis
Analysis Oncology Pharmacy Hypothesis-generating Grade: Low
Also in Gastroenterology / Hepatology

Pembrolizumab outshines others in post-TKI hepatocellular carcinoma treatment.

De-escalation in Severe Abdominal Sepsis: Association With Cure, Not Proof of Benefit
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Low
Also in Critical Care / ICU, Gastroenterology / Hepatology

De-escalation boosts survival in severe intra-abdominal infections.

Subcutaneous Vedolizumab Holds Its Own Against Newer UC Therapies in Network Meta-Analysis
Analysis Rheumatology / Immunology Hypothesis-generating Grade: Low
Also in Gastroenterology / Hepatology

Vedolizumab SC shines in efficacy and safety for ulcerative colitis.

App-Guided Tapering Raises PPI Discontinuation From 64% to 86% Versus Brochure
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low

App proves superior in discontinuing unnecessary PPI use.

Sofosbuvir/Daclatasvir Matches Grazoprevir/Elbasvir at 100% SVR12 in Hemodialysis Hepatitis C
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low

Sofosbuvir/daclatasvir proves effective for hepatitis C in hemodialysis patients.

IBC Superior for Liver Metastasis in Lung Cancer
Analysis Gastroenterology / Hepatology

New treatments show promise for liver metastases in lung cancer.

Vedolizumab-First in UC Linked to More Steroid-Free Stability
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low

Vedolizumab delivers better long-term stability in UC than TNF antagonists.

Biologics and JAK inhibitors show efficacy in Crohn's-associated orofacial granulomatosis
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low
Also in Rheumatology / Immunology

Biologics show promise for Crohn's disease with orofacial granulomatosis.

AASLD/IDSA 2025 Hepatitis B Guideline Shifts From Guidance to Recommendations
Guideline Infectious Disease / Antimicrobials Practice-changing Grade: Low
Also in Gastroenterology / Hepatology

New guidelines reshape hepatitis B virus management strategies.

Short-Course Steroids Trigger HBV Reactivation in COVID-19
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Very Low

Screen for HBV before giving corticosteroids to COVID-19 patients.

Risankizumab in IBD: Effective but Evidence Uneven Across CD and UC
Analysis Gastroenterology / Hepatology Confirmatory Grade: Low
Also in Rheumatology / Immunology

Risankizumab shows promise for challenging Crohn's and colitis cases.

Pediatric Peptic Ulcer Disease: Scope-and-Treat, Not Test-and-Treat
Analysis Pediatric Pharmacy Confirmatory Grade: Low
Also in Gastroenterology / Hepatology

Pediatric peptic ulcer disease demands tailored management strategies beyond adult protocols.

Bilirubin-Guided Voriconazole Dosing Improves Target Attainment in Liver Dysfunction
Analysis Pharmacokinetics / TDM Hypothesis-generating Grade: Low
Also in Gastroenterology / Hepatology

Optimized voriconazole dosing enhances outcomes in liver dysfunction.