PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

131 articles indexed across 16 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 12 from 1 topic.Sort: Newest | Oldest
Dexmedetomidine vs Clonidine vs Propofol: Extubation in ICU Patients
🔓 Free Teaser Critical Care / ICU

The A2B trial evaluates sedation strategies on extubation timing in critical care.

Half of Immunocompromised Sepsis Patients Lack Bacterial Infection
Critical Care / ICU Hypothesis-generating Grade: Low

Immunocompromised sepsis patients often lack bacterial infection confirmation.

REDUCE-1 Pilot: Restrictive Fluids Safe But Failed Feasibility in PICU
Critical Care / ICU Inconclusive Grade: Low

Can restrictive fluid protocols improve outcomes in PICU patients?

No Mortality Advantage for Higher-Dose Steroids in Pneumonia
Critical Care / ICU Confirmatory Grade: Low

Lower and higher corticosteroid doses both reduce pneumonia mortality.

Higher MAP Targets Raise Pulmonary Pressures and RV Workload Post-Arrest
Critical Care / ICU Confirmatory Grade: Moderate

Higher blood pressure targets optimize circulation in cardiac arrest survivors.

REMAP-CAP: Ivermectin Fails to Help Hospitalized COVID-19 Patients
Critical Care / ICU Confirmatory Grade: Low

Ivermectin fails to enhance survival in hospitalized COVID-19 cases.

Sepsis survivors carry elevated psychiatric risk for five years
Critical Care / ICU Confirmatory Grade: Moderate

Sepsis survivors face an increased risk of developing psychiatric disorders.

Invasive Candidiasis in the ICU: Diagnosis, Echinocandins, Resistance
Critical Care / ICU Confirmatory Grade: Low

Invasive candidiasis is a deadly ICU complication needing swift action.

Brain-Focused Critical Care Extends NIDCAP Beyond the NICU
Critical Care / ICU Hypothesis-generating Grade: Low

Shifting pediatric critical care towards brain-focused outcomes.

Gaps in VAP Prevention Knowledge Among ICU Staff
Critical Care / ICU

Education gaps in VAP prevention hinder ICU care quality.

SDD Linked to Increased Tobramycin Resistance in E. coli
Critical Care / ICU

SDD increases tobramycin resistance gene prevalence in E. coli.

Surviving Sepsis Campaign 2026 Guidelines Overhaul Adult Sepsis Management
Critical Care / ICU Practice-changing Grade: Moderate

2026 sepsis guidelines enhance antimicrobial and fluid strategies.