PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

309 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 11 from 1 topic.Sort: Newest | Oldest
Oral Ketamine as a Practical, Low-Cost Option for Severe Depression
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Very Low

Oral ketamine emerges as a safe, low-cost depression treatment.

Starting Regimen Predicts Early ADHD Treatment Instability in Adults
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Low

ADHD treatment choice influences medication stability in Japanese adults.

Psilocybin Feasible for Treatment-Resistant Depression in NHS Setting
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Low

Psilocybin shows promise for treatment-resistant major depression.

Esketamine Reduces Depression in At-Risk Adolescents
Analysis Psychiatry / Psychopharmacology

Esketamine shows promise in quickly reducing severe depression in high-risk adolescents.

Network Meta-Analysis Ranks 21 Antidepressants for Acute Depression
Analysis Psychiatry / Psychopharmacology Practice-changing Grade: Moderate

Antidepressants show varied efficacy and acceptability for major depressive disorder.

Dose-Specific Network Meta-Analysis Reaffirms Antipsychotics for Acute Mania
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low

Risperidone tops the list for acute bipolar mania efficacy.

DISCARD Trial: Linear vs Hyperbolic Antidepressant Tapering Protocol
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Very Low

Exploring safer ways to stop antidepressants in remitted depression.

Modeling Supports One-Day Oral Overlap for Aripiprazole LAI Start in Japan
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low

New aripiprazole regimen may enhance adherence in schizophrenia and bipolar I disorder.

Oral Prolonged-Release Ketamine Misses Primary Endpoint, Avoids Dissociation
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Low

Oral KET01 potentially offers safer, at-home depression treatment.

Esketamine Monotherapy Shows Rapid Efficacy in Treatment-Resistant Depression
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Moderate

Esketamine offers new hope for treatment-resistant depression monotherapy.

Fixed Low-Dose Oral Esketamine Fails in Treatment-Resistant Depression
Analysis Psychiatry / Psychopharmacology Inconclusive Grade: Low

Oral esketamine may be effective only at higher doses for resistant depression.