PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

538 articles indexed across 24 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 26 from 1 topic.Sort: Newest | Oldest
ADHD Carries Excess Mortality; Medication Link Rests on Three Studies
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low

ADHD medications may lower mortality risk, study finds.

Polish Psychiatric Association Guides Metabolic Risk Management in Antipsychotic Users
★ Editor's Pick Guideline Psychiatry / Psychopharmacology Practice-changing Grade: Moderate
Also in Endocrinology / Obesity

Prevent metabolic disorders in patients on antipsychotics with early screening and metformin.

Montelukast Linked to Higher ADHD and Conduct Risk Versus Inhaled Steroids
Analysis Pediatric Pharmacy Confirmatory Grade: Low
Also in Psychiatry / Psychopharmacology

Montelukast may increase neuropsychiatric risks in children with asthma.

Psilocybin in Depression: Mechanistic Breadth, Clinical Promise, Weak Certainty
★ Editor's Pick Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Low

Psilocybin rapidly alleviates treatment-resistant depression symptoms.

Only One in Five Young Adults Adhere After First Psychosis
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low

First-episode psychosis patients show alarmingly low antipsychotic adherence.

Xanomeline-Trospium: A Muscarinic Alternative to Dopamine Blockade
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Moderate

Cobenfy offers a novel way to treat schizophrenia with fewer side effects.

LAIAs help intellectual disability patients with SMI, not off-label behavior
Analysis Geriatrics / Geriatric Pharmacy Hypothesis-generating Grade: Low
Also in Psychiatry / Psychopharmacology

LAIAs show promise for PWID with schizophrenia or bipolar disorder, but caution is needed for others.

Neurosteroids reshape postpartum depression care: brexanolone to zuranolone
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low
Also in Women's Health / Reproductive

Brexanolone and zuranolone redefine postpartum depression treatment with rapid action.

Non-Psychotropic Polypharmacy Rises With Age in Psychiatric Inpatients
Analysis Geriatrics / Geriatric Pharmacy Hypothesis-generating Grade: Low
Also in Psychiatry / Psychopharmacology

Non-psychotropic polypharmacy in psychiatric patients rises with age and comorbidities.

Ketamine for Treatment-Resistant Bipolar Depression: Stratify, Monitor, Maintain
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Very Low

Ketamine infusions may offer rapid relief in TRBPD but need tailored maintenance plans.

Oral Ketamine as a Practical, Low-Cost Option for Severe Depression
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Very Low

Oral ketamine emerges as a safe, low-cost depression treatment.

Starting Regimen Predicts Early ADHD Treatment Instability in Adults
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Low

ADHD treatment choice influences medication stability in Japanese adults.

Half of children with ADHD adhere to prescribed medication
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low
Also in Pediatrics

Adherence to ADHD medication is only 43.6% in youth.

Psilocybin Feasible for Treatment-Resistant Depression in NHS Setting
Analysis Psychiatry / Psychopharmacology Hypothesis-generating Grade: Low

Psilocybin shows promise for treatment-resistant major depression.

Esketamine Reduces Depression in At-Risk Adolescents
Analysis Psychiatry / Psychopharmacology

Esketamine shows promise in quickly reducing severe depression in high-risk adolescents.