Clinical Specialty Index

Automated Plasma p-tau217 Accurately Detects Alzheimer Pathology Across Care Settings
Analysis Neurology / Neuropharmacology Practice-changing Grade: High

This multicohort validation gives neurology pharmacists concrete accuracy, cutoff, and workflow data for a scalable blood test that can gate amyloid-targeting therapy eligibility.

Tenecteplase Boosts Late-Window Reperfusion but Not 90-Day Function
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Low

Tenecteplase enhances late-window stroke reperfusion without added hemorrhage risk.

Blood Biomarker Guideline Sets Accuracy Thresholds for Alzheimer's Workup
Analysis Neurology / Neuropharmacology Confirmatory Grade: Low

This Alzheimer's Association guideline gives pharmacists concrete sensitivity and specificity thresholds for judging whether a plasma Alzheimer's test is fit for triaging or confirmatory use in specialty memory care.

TIMELESS: Late-Window Tenecteplase Fails to Improve Stroke Outcomes
Analysis Neurology / Neuropharmacology Confirmatory Grade: High

Tenecteplase fails to outperform placebo in delayed stroke treatment.

Perfusion-Selected Alteplase Extends Thrombolysis Window to 9 Hours
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Moderate

Alteplase shows promise for late-presenting stroke when guided by imaging.

MRI Mismatch Extends Alteplase to Unknown-Onset Stroke
Analysis Neurology / Neuropharmacology Practice-changing Grade: Moderate

MRI-guided thrombolysis may benefit stroke of unknown onset.