Blood Biomarker Guideline Sets Accuracy Thresholds for Alzheimer's Workup

This Alzheimer's Association guideline gives pharmacists concrete sensitivity and specificity thresholds for judging whether a plasma Alzheimer's test is fit for triaging or confirmatory use in specialty memory care.

blood-based biomarkersplasma p-tau217p-tau181amyloid-beta 42/40Alzheimer's diseaseclinical practice guidelineGRADEdiagnostic test accuracyamyloid PETcerebrospinal fluid biomarkersmemory disordersneuropharmacology Neurology / Neuropharmacology

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Authors: Palmqvist S, Whitson HE, Allen LA, Suarez-Calvet M, Galasko D, Karikari TK, Okrahvi HR, Paczynski M, Schindler SE, Teunissen CE, Zetterberg H, Carrillo MC, Edelmayer RM, Mahinrad S, McAteer MB, Kahale LA, Pahlke S, Tampi MP

Citation: Palmqvist S, Whitson HE, Allen LA, et al. Alzheimer's Association Clinical Practice Guideline on the use of blood-based biomarkers in the diagnostic workup of suspected Alzheimer's disease within specialized care settings. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(7):e70535. doi:10.1002/alz.70535

Article Links: PubMed · Journal / DOI · Free Full Text (PMC)

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