PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

463 articles indexed across 24 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 15 from 1 topic.Sort: Newest | Oldest
Rapid IV Opioid Titration Delivers Fast Relief in Palliative Crises
Analysis Palliative Care Confirmatory Grade: Very Low
Also in Pain Management

Rapid opioid titration swiftly eases acute crises in palliative care with minimal side effects.

Buprenorphine initiation in fentanyl use: Practical strategies for family physicians
★ Editor's Pick Analysis Pain Management Confirmatory Grade: Low

Flexible buprenorphine strategies enhance fentanyl treatment in primary care.

Perioperative Nicotine Withdrawal Amplifies Pain and Opioid Demand
Analysis Perioperative / Anesthesia Hypothesis-generating Grade: Low
Also in Pain Management

Nicotine withdrawal heightens pain, increasing opioid needs post-surgery.

Australian pharmacies now stock naloxone widely, knowledge drives supply
Analysis Pain Management Confirmatory Grade: Low
Also in Behavioral Health / Addiction Medicine

Positive pharmacist attitudes drive naloxone availability in Australia.

Oliceridine Matches Sufentanil, Halves Nausea After Abdominal Surgery
Analysis Perioperative / Anesthesia Confirmatory Grade: Moderate
Also in Pain Management

Oliceridine matches sufentanil for pain relief, reduces nausea.

Ketamine Beats Lidocaine Early but Not at Six Months
Analysis Pain Management Hypothesis-generating Grade: Low

Ketamine offers early pain relief for chronic neuropathic pain.

Methadone Beats Buprenorphine-Naloxone for 1-Year Survival After Overdose
★ Editor's Pick Analysis Pain Management Hypothesis-generating Grade: Low
Also in Behavioral Health / Addiction Medicine

Methadone shows improved survival in opioid overdose survivors.

Pregabalin Adds No Benefit to Transdermal Buprenorphine in Neuropathic Pain
Analysis Pain Management Confirmatory Grade: Moderate

Pregabalin and buprenorphine fail to ease neuropathic pain effectively.

Ketamine Versus Pregabalin for Opioid Sparing After Spinal Fusion
★ Editor's Pick Analysis Perioperative / Anesthesia Hypothesis-generating Grade: Low
Also in Pain Management, Pharmacokinetics / TDM

Ketamine might outperform pregabalin in reducing opioid use post-spinal fusion.

Liposomal Bupivacaine Cuts Movement Pain After CRS + HIPEC
Analysis Perioperative / Anesthesia Hypothesis-generating Grade: Low
Also in Pain Management

Can liposomal bupivacaine revolutionize post-surgical pain management in CRS + HIPEC?

Psychosocial Complexity Does Not Predict Withdrawal During Methadone-Buprenorphine Transfer
Analysis Pain Management Hypothesis-generating Grade: Low

Withdrawal during methadone-to-buprenorphine transfers peaks and is predictable.

Buprenorphine-Naloxone Cuts Nonfatal Overdose vs XR Naltrexone Post-Withdrawal
Analysis Pain Management Confirmatory Grade: Moderate

Buprenorphine-naloxone reduces overdose risk more effectively than XR naltrexone.

North Carolina Pharmacists Ambivalent but Willing on Methadone Dispensing
Analysis Pain Management Hypothesis-generating Grade: Low

Pharmacists willing but cautious with methadone services for OUD.

First OAA Guidance Standardizes Remifentanil PCA for Labour Analgesia
Guideline Pain Management Practice-changing Grade: Low
Also in Women's Health

New guidelines aim to standardise remifentanil PCA for labour analgesia.

Opioid-Sparing and Opioid-Free Anaesthesia: A Practical Implementation Review
Analysis Perioperative / Anesthesia Confirmatory Grade: Low
Also in Pain Management

Opioid-free anaesthesia speeds recovery and slashes opioid use.