Sofosbuvir/Velpatasvir Handles Novel Hepatitis C Subtypes; Genotype 3b Remains a Concern
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Han WM, Solomon S, Wagner-Cardoso S, et al.
Oct 24, 2026 · Published in: Journal of Viral Hepatitis
Also in Gastroenterology / Hepatology
SOF/VEL shows promise against diverse HCV genotypes, including novel subtypes.
De-escalation in Severe Abdominal Sepsis: Association With Cure, Not Proof of Benefit
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Low
Zhang L, Ye H
Oct 23, 2026 · Published in: BMC Infectious Diseases
Also in Critical Care / ICU, Gastroenterology / Hepatology
De-escalation boosts survival in severe intra-abdominal infections.
Bayesian Tobramycin Dosing in Cystic Fibrosis Exposes Hidden Underexposure
Analysis Pharmacokinetics / TDM Hypothesis-generating Grade: Very Low
Johnson E, Williams M, Henderson D, et al.
Oct 18, 2026 · Published in: European Journal of Clinical Pharmacology
Also in Infectious Disease / Antimicrobials
Bayesian TDM redefines tobramycin dosing in cystic fibrosis.
Gepotidacin Delivers Early Symptom Relief in Uncomplicated Cystitis
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Ramírez M, Gupta K, Díaz-Regañón J, et al.
Sep 29, 2026 · Published in: JAMA Network Open
Gepotidacin quickly alleviates urinary tract infection symptoms.
Pharmacist Prescribing for ED Culture Callbacks: 11-Month CPA Implementation Report
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Very Low
Miles B, Alkhatib S, Eimen M, et al.
Sep 28, 2026 · Published in: Journal of the American Pharmacists Association : JAPhA
Also in Clinical Practice
Pharmacist-led antibiotic management streamlines emergency department culture follow-up.
Presenting Symptoms Shape Antibiotic Timing in Community-Onset Sepsis
★ Editor's Pick Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Conlon A, Seelye S, Walzl E, et al.
Sep 28, 2026 · Published in: JAMA Network Open
Also in Critical Care / ICU
Early antibiotics in sepsis save lives, regardless of symptoms.
P-CABs Outperform PPIs in Clarithromycin-Resistant H. pylori
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Andreev DN, Khurmatullina AR, Bordin DS, et al.
Sep 26, 2026 · Published in: Pathogens (Basel, Switzerland)
P-CABs are more effective than PPIs against resistant Helicobacter pylori.
Partial Oral Antibiotic Therapy for Endocarditis: 2023 ESC Framework Reviewed
★ Editor's Pick Guideline Infectious Disease / Antimicrobials Practice-changing Grade: Moderate
Roland T, Yombi JC
Sep 26, 2026 · Published in: Pathogens (Basel, Switzerland)
POAT reduces hospital stay and mortality in selected IE patients.
Aztreonam/Avibactam Fills the Metallo-β-Lactamase Treatment Gap
★ Editor's Pick Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Zhou J, Weng R, Ye Y, et al.
Sep 23, 2026 · Published in: Emerging Microbes & Infections
Aztreonam/Avibactam targets metallo-β-lactamase-producing bacteria, addressing a critical resistance challenge.
Antibiotic Substitution Ends Decade-Long NICU Tobramycin-Resistant S. aureus Outbreak
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Very Low
Jogenfors A, Mernelius S, Löfgren S, et al.
Sep 22, 2026 · Published in: BMC Infectious Diseases
Targeted interventions halted a decade-long resistant bacteria outbreak in a NICU.
Pharmacist Review of Pending Infection Tests Raises Appropriate Post-Discharge Antimicrobial Use
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Low
Covington EW, Loop MS, Park J, et al.
Sep 21, 2026 · Published in: Open Forum Infectious Diseases
Also in Ambulatory Care / MTM, Clinical Practice
Pharmacists boost antimicrobial appropriateness post-discharge by 23% in a week.
Single-Dose Prophylaxis Noninferior to Multiple Doses in Hip Arthroplasty
Analysis Perioperative / Anesthesia Confirmatory Grade: Moderate
Abedi AA, Anneberg M, Pedersen AB, et al.
Sep 18, 2026 · Published in: JAMA Network Open
Also in Infectious Disease / Antimicrobials
Single antibiotic dose matches multiple doses in hip surgery infection prevention.
Unit Colonization Pressure Drives Neonatal ESBL Gut Acquisition
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Cook A, Berkell M, van Werkhoven CH, et al.
Sep 15, 2026 · Published in: JAMA Network Open
ESBL colonization pressure boosts infant infection risk in neonatal units.
Low-dose clindamycin viable for non-S. aureus prosthetic joint infection
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Low
Ericsson J, Gustafsson T, Sköldenberg O, et al.
Sep 12, 2026 · Published in: BMC Infectious Diseases
Clindamycin is effective for prosthetic joint infections, though less so for Staphylococcus aureus.
Lenacapavir and Fostemsavir in Multidrug-Resistant HIV-1: Real-World Data
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Very Low
Boujamline S, Boschi C, Bes-Barlandier H, et al.
Sep 11, 2026 · Published in: Journal of Medical Virology
New HIV drugs show promise for resistant cases in France.