Pharmacist Prescribing for ED Culture Callbacks: 11-Month CPA Implementation Report

This single-site practice report describes how an emergency department (ED) collaborative practice agreement (CPA) enabled pharmacist antibiotic prescribing after discharge, offering a process template but no clinical outcome data.

📅 Journal publication: Sep 28, 2026 · Last updated: Oct 25, 2026

collaborative practice agreementantimicrobial stewardshipemergency departmentculture follow-uppharmacist prescribingurinary tract infectionESBLnitrofurantointrimethoprim-sulfamethoxazolepractice innovation reportprocess evaluation Infectious Disease / Antimicrobials

Also in Clinical Practice

Background Information

Pharmacist-led antibiotic management streamlines emergency department culture follow-up.

Implementing pharmacist-led antibiotic management in emergency departments (EDs) can enhance antimicrobial stewardship and workflow efficiency. After implementing the collaborative practice agreement (CPA), 898 interventions were recorded with 100% protocol compliance by pharmacists. This model expands pharmacist roles in EDs, demonstrating feasibility and protocol adherence, but limited to a single hospital setting. Empowering pharmacists with prescribing authority improves ED antibiotic management and protocol compliance.

📊 Deep Analysis Available

Subscribers get the full breakdown: study design, outcomes, pharmacist implications, clinical pearls, GRADE evidence grade, and a downloadable PDF report.

Subscribe for Full Access →

Authors: Miles B, Alkhatib S, Eimen M, Keeys C, Norris P

Citation: Miles B, Alkhatib S, Eimen M, et al. Advancing antimicrobial stewardship with streamlining pharmacist management of culture results through implementation of a collaborative practice agreement in a community hospital emergency department. Journal of the American Pharmacists Association : JAPhA. 2026:103534. doi:10.1016/j.japh.2026.103534

Article Links: PubMed · Journal / DOI

🎓

Reviewed by a licensed pharmacist

Every analysis is reviewed and approved by a licensed pharmacist before publication, ensuring clinical accuracy and relevance.

Accurate and up-to-date information is our highest priority.

If you spot an error, please suggest a correction. If there is a topic you want covered, tell us and we will look at it.

Suggest a correction Request a topic

Thanks for the feedback!

🔒

Deep Analysis: Subscribers Only

Subscribers receive access to a complete clinical analysis, available online and as a downloadable PDF.

Executive Summary

Study Design

Patient Population

Primary Outcomes

Secondary Outcomes & Safety Profile

Pharmacist Implications

Clinical Pearls

Limitations

Controversies & Evidence Gaps

Cost & Logistics

Want the full analysis?

Subscribe to PharmD Signal for unrestricted access to every deep analysis, plus PDF reports, GRADE evidence grades, and pharmacist implications for every article we publish.

Become a Subscriber →