PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

309 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

New EULAR guidelines redefine RA management with DMARDs.

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Showing 32 from 1 topic.Sort: Newest | Oldest
2026 Dyslipidemia Guideline: Target-Driven Therapy and the End of the Nonstatin Stepladder
🔓 Free Teaser Reference Card Cardiology / Anticoagulation

How the 2026 ACC/AHA guideline changes lipid clinic workflows with absolute LDL-C targets, non-sequential nonstatin selection, and universal Lp(a) testing.

In-Hospital Dapagliflozin Misses Primary Endpoint but Mortality Signal Persists
🔓 Free Teaser Analysis Cardiology / Anticoagulation Confirmatory Grade: Moderate

The largest, most rigorous trial of in-hospital sodium-glucose cotransporter-2 inhibitor initiation was formally neutral, but pooled trial data continue to support early inpatient start for hospitalized heart failure patients.

ACC/AHA Introduces Precision Lipidology for ASCVD
Guideline Cardiology / Anticoagulation

Dramatic shift to precision lipidology in ASCVD prevention.

DOAC dosing alerts corrected only one-third of errors
Analysis Cardiology / Anticoagulation Hypothesis-generating Grade: Low

Tailored alerts improve correction of DOAC dosing errors.

Fragile Efficacy Signals Underlie DOACs for Cancer-Associated VTE
Analysis Cardiology / Anticoagulation Confirmatory Grade: Moderate

DOACs for cancer thrombosis: Efficacy vs. bleeding risk.

OAC Monotherapy Cuts Bleeding Without Ischemic Penalty in CCS
Analysis Cardiology / Anticoagulation Confirmatory Grade: Moderate

OAC monotherapy reduces bleeding in CCS without adding ischemic risk.

DOACs Linked to Lower Stroke and Bleeding in Elderly AF
Analysis Cardiology / Anticoagulation Confirmatory Grade: Low

DOACs safely reduce stroke risk in elderly AF patients.

2026 Dyslipidemia Guideline Adds 25 Million Statin Candidates
Analysis Cardiology / Anticoagulation Confirmatory Grade: Moderate

2026 guidelines expand statin eligibility for millions of adults.

DOAC After LAAC Beats DAPT Only in Observational Data
Analysis Cardiology / Anticoagulation Inconclusive Grade: Low

DOACs may outperform DAPT after LAAC in NVAF patients.

Early In-Hospital ARNI After MI: Promising but PARADISE-MI Anchors Caution
Analysis Cardiology / Anticoagulation Hypothesis-generating Grade: Low

Early ARNI therapy post-AMI cuts cardiovascular events by 42%.

DOAC Dosing in CKD/ESRD: Apixaban Leads, But the Evidence Is Thin
Reference Card Cardiology / Anticoagulation

A pharmacist's guide to DOAC selection, dosing, and the inappropriate dose reduction problem in renal impairment.

No Advantage for Rhythm Control in Post-Cardiac Surgery AF
Analysis Cardiology / Anticoagulation Confirmatory Grade: Very Low

Rhythm control offers no clear advantage over rate control post-cardiac surgery.

ACE Inhibitors Beat ARBs for Cardiovascular Mortality in High-Risk Patients
Analysis Cardiology / Anticoagulation Confirmatory Grade: Moderate

ACE inhibitors outperform ARBs in reducing heart risks.

Hospital-Wide AF Alert System Boosts Anticoagulation Adherence, Cuts Stroke
Analysis Cardiology / Anticoagulation Confirmatory Grade: Low

Hospital-wide AF screening enhances anticoagulation guidelines adherence, reduces strokes.

Acoramidis Slows Health Status Decline in ATTR-CM
Analysis Cardiology / Anticoagulation Confirmatory Grade: High

Acoramidis significantly improves quality of life for ATTR-CM patients.