International Hypertension Guidelines in CKD: ESH, ESC, KDIGO, and AHA/ACC Compared
This narrative review maps where the four major hypertension guidelines converge and diverge for CKD patients, clarifying practical implications for BP targets, RAS inhibition, diuretic selection, and cardio-renal add-on therapies.
Navigating global hypertension guidelines in CKD can enhance patient care.
Hypertension management in chronic kidney disease (CKD) is crucial due to the increased cardiovascular risk associated with condition severity. Guidelines agree on dual-agent therapy using renin-angiotensin system inhibitors with either calcium-channel blockers or diuretics, emphasizing the consideration of renal function in therapy selection. Clinicians must navigate varying global guidelines on hypertension in CKD, focusing on a patient-centered and cardio-renal protective approach. Understanding diverse guideline recommendations aids in optimizing hypertension management for CKD patients.
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Authors:Stambolliu E, Stathopoulou E, Bora M, Damianaki A
Citation:Stambolliu E, Stathopoulou E, Bora M, et al. Hypertension in chronic kidney disease: where do international guidelines converge and diverge?. Clinical hypertension. 2026;32:e32. doi:10.5646/ch.2026.32.e32
Subscribers receive access to a complete clinical analysis, available online and as a downloadable PDF.
Executive Summary
Study Design
Patient Population
Primary Outcomes
Secondary Outcomes & Safety Profile
Pharmacist Implications
Clinical Pearls
Limitations
Controversies & Evidence Gaps
Cost & Logistics
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