Brain Trauma Foundation 4th Edition Severe TBI Guidelines Reshape Neurocritical Practice
🔓 Free Teaser Guideline Traumatic Brain Injury Practice-changing Grade: Moderate
Published in: Brain Trauma Foundation / Neurosurgery
The BTF 4th Edition revises hyperosmolar, seizure, steroid, ICP-threshold, and sedation guidance most relevant to neuro-ICU pharmacists.
Mirikizumab Sustains Four-Year Remission in Ulcerative Colitis Responders
Analysis Rheumatology / Immunology Confirmatory Grade: Low
Owens HN, Vázquez-Otero C, Arevalo M, et al.
Dec 7, 2026 · Published in: Human Vaccines & Immunotherapeutics
Also in Gastroenterology / Hepatology
Provider training can drive HPV vaccine uptake in young adults.
Sofosbuvir/Velpatasvir Handles Novel Hepatitis C Subtypes; Genotype 3b Remains a Concern
Analysis Infectious Disease / Antimicrobials Confirmatory Grade: Low
Han WM, Solomon S, Wagner-Cardoso S, et al.
Oct 24, 2026 · Published in: Journal of Viral Hepatitis
Also in Gastroenterology / Hepatology
SOF/VEL shows promise against diverse HCV genotypes, including novel subtypes.
Second-Line HCC After TKI Failure: Efficacy Versus Toxicity Network Analysis
Analysis Oncology Pharmacy Hypothesis-generating Grade: Low
Li X, Nie G, Wang Y, et al.
Oct 24, 2026 · Published in: Frontiers in Immunology
Also in Gastroenterology / Hepatology
Pembrolizumab outshines others in post-TKI hepatocellular carcinoma treatment.
De-escalation in Severe Abdominal Sepsis: Association With Cure, Not Proof of Benefit
Analysis Infectious Disease / Antimicrobials Hypothesis-generating Grade: Low
Zhang L, Ye H
Oct 23, 2026 · Published in: BMC Infectious Diseases
Also in Critical Care / ICU, Gastroenterology / Hepatology
De-escalation boosts survival in severe intra-abdominal infections.
Subcutaneous Vedolizumab Holds Its Own Against Newer UC Therapies in Network Meta-Analysis
Analysis Rheumatology / Immunology Hypothesis-generating Grade: Low
Jiang J, Wojtowicz A, Uyei J, et al.
Oct 22, 2026 · Published in: BMC Gastroenterology
Also in Gastroenterology / Hepatology
Vedolizumab SC shines in efficacy and safety for ulcerative colitis.
Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer: Survival Benefit Varies by Setting
Analysis Oncology Pharmacy Confirmatory Grade: Moderate
Guan B, Chen Y, Zhou R, et al.
Oct 22, 2026 · Published in: Frontiers in Immunology
PD-1/PD-L1 inhibitors boost survival in triple-negative breast cancer.
Dupilumab in Young Children With Atopic Dermatitis: Single-Center Real-World Efficacy and Basophil Signal
Analysis Pediatric Pharmacy Hypothesis-generating Grade: Very Low
Ma L, Wei M, Mou W, et al.
Oct 21, 2026 · Published in: BMC Pediatrics
Dupilumab shows promise for young children with severe eczema.
Ivonescimab Plus Chemotherapy for Post-Escalation EGFR-Mutated NSCLC Leptomeningeal Metastases: Retrospective Signal
Analysis Oncology Pharmacy Hypothesis-generating Grade: Very Low
Wu Q, Qiu L, An J, et al.
Oct 20, 2026 · Published in: Frontiers in Immunology
Exploring ivonescimab as salvage therapy for advanced NSCLC challenges.
App-Guided Tapering Raises PPI Discontinuation From 64% to 86% Versus Brochure
Analysis Gastroenterology / Hepatology Hypothesis-generating Grade: Low
Koggel LM, Timmers T, Lantinga MA, et al.
Oct 19, 2026 · Published in: United European Gastroenterology Journal
App proves superior in discontinuing unnecessary PPI use.
ADHD Carries Excess Mortality; Medication Link Rests on Three Studies
Analysis Psychiatry / Psychopharmacology Confirmatory Grade: Low
Corrigan L, Heywood L, Stewart GR, et al.
Oct 19, 2026 · Published in: JAMA Network Open
ADHD medications may lower mortality risk, study finds.
Initial Back Pain Treatment Choice Shifts Later Opioid Use Disorder Risk
Analysis Pain Management Confirmatory Grade: Low
Doan LV, Hung AM, Olfson M, et al.
Oct 19, 2026 · Published in: JAMA Network Open
Nonpharmacologic treatments cut opioid use disorder risk by 32.8%.
One in Four Carboplatin Shortage Allocations Missed Policy Intent
★ Must Read Analysis Oncology Pharmacy Hypothesis-generating Grade: Low
Blackstone EC, Wang Y, Inyang EA, et al.
Oct 19, 2026 · Published in: JAMA Network Open
Addressing chemotherapy shortages reveals critical allocation policy gaps.
Bayesian Tobramycin Dosing in Cystic Fibrosis Exposes Hidden Underexposure
Analysis Pharmacokinetics / TDM Hypothesis-generating Grade: Very Low
Johnson E, Williams M, Henderson D, et al.
Oct 18, 2026 · Published in: European Journal of Clinical Pharmacology
Also in Infectious Disease / Antimicrobials
Bayesian TDM redefines tobramycin dosing in cystic fibrosis.
Narrative Review Maps Incretin Obesity Therapy: Efficacy Hierarchy, Safety, and Pipeline Agents
Analysis Endocrinology / Diabetes / Obesity Confirmatory Grade: Low
Bartkowiak D, Jakubczyk B, Lasota A, et al.
Oct 17, 2026 · Published in: Cureus
GLP-1 and GIP agonists redefine obesity treatment possibilities.