PharmD Signal

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🧠 Clinical library

Clinical Specialty Index

314 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

Showing all 314 articles.Sort: Newest | Oldest
Mirikizumab sustains multidomain UC remission through four years
Analysis Gastroenterology / Hepatology Confirmatory Grade: Low

Four-year study shows lasting ulcerative colitis remission with mirikizumab.

ESC and EACTS Issue Consensus on Antithrombotic Therapy After CABG
Consensus Statement Cardiology / Anticoagulation Inconclusive Grade: Low

Balance risks: Antithrombotic therapy post-bypass under scrutiny.

Daraxonrasib Shows Early Activity in RAS-Mutated Pancreatic Cancer
Analysis Oncology Pharmacy Hypothesis-generating Grade: Low

Daraxonrasib shows promise in advanced RAS-mutated pancreatic cancer.

Semaglutide cuts heavy drinking in alcohol use disorder with obesity
Analysis Behavioral Health / Addiction Medicine Hypothesis-generating Grade: Moderate

Semaglutide reduces alcohol intake in comorbid obesity.

AASLD Adds Semaglutide to MASH Practice Guidance With NIT-Based Selection
Guideline Gastroenterology / Hepatology Practice-changing Grade: Moderate

Semaglutide offers new hope for MASH management with significant fibrosis improvement.

Asundexian Cuts Recurrent Stroke Without Excess Bleeding
Analysis Cardiology / Anticoagulation Practice-changing Grade: High

Could a new anticoagulant improve stroke prevention?

KRAS Inhibitors May Unlock Immunotherapy in Pancreatic Cancer
Analysis Oncology Pharmacy Hypothesis-generating Grade: Very Low

KRAS inhibitors may revolutionize immunotherapy for pancreatic cancer.

Surviving Sepsis Campaign 2026 Guidelines Overhaul Adult Sepsis Management
Guideline Critical Care / ICU Practice-changing Grade: Moderate

2026 sepsis guidelines enhance antimicrobial and fluid strategies.

Atezolizumab Plus FOLFOX Halves Recurrence in dMMR Stage III Colon Cancer
Analysis Oncology Pharmacy Practice-changing Grade: High

Atezolizumab enhances survival in dMMR colon cancer.

Obinutuzumab Improves Response in Active Non-Renal SLE
Analysis Rheumatology / Immunology Practice-changing Grade: High

Obinutuzumab improves SLE outcomes in the recent ALLEGORY trial.

Biomarker Strategies for Chemotherapy Cardiotoxicity: Promise Versus Validation
Analysis Oncology Pharmacy Confirmatory Grade: Very Low

New biomarkers offer promise for early detection of chemotherapy-induced heart damage.

Plasma p-tau217 Clocks Estimate Timing of Alzheimer Symptom Onset
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Moderate

This work demonstrates that a single blood-based %p-tau217 measurement can estimate not only whether but approximately when a cognitively unimpaired person will develop symptomatic Alzheimer disease, with implications for how pharmacists interpret emerging blood biomarker tests and screen for anti-amyloid therapy candidates.

ADA Standards of Care: Pharmacologic Treatment of Obesity in Adults
Guideline Obesity / Weight Management Practice-changing Grade: Moderate

The ADA's new Obesity Association guideline reframes obesity pharmacotherapy around treating obesity-related diseases rather than weight targets alone, elevates GLP-1RA and dual GIP/GLP-1RA agents to preferred status across multiple comorbidities, and mandates indefinite continuation to prevent weight recurrence.

Resmetirom Update: Positioning the First Approved MASH Therapy
Analysis Gastroenterology / Hepatology Confirmatory Grade: Moderate

Resmetirom is the first drug to reverse MASH and fibrosis.

Active Pharmacist Ward Integration Outperforms Education in Renal Prescribing
Analysis Medication Safety Hypothesis-generating Grade: Low

Pharmacist interventions cut drug-related issues by 30% in renal patients.