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Clinical Specialty Index

314 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

Showing all 314 articles.Sort: Newest | Oldest
AHA/ASA Releases 2022 Guideline for Management of Spontaneous Intracerebral Hemorrhage
Guideline Hemorrhagic Stroke Practice-changing Grade: High

The guideline introduces significant updates in blood pressure management and anticoagulation reversal strategies for ICH.

Tirzepatide Delivers Up to 21% Weight Loss in Obesity
Analysis Endocrinology / Diabetes / Obesity Practice-changing Grade: High

Tirzepatide delivers unprecedented weight loss results in obesity management.

GINA 2021: Two-Track Asthma Strategy Replaces SABA-Only Reliever Reliance
Guideline Asthma Practice-changing Grade: Moderate

GINA 2021 formalizes ICS-formoterol as the preferred reliever across all adult/adolescent steps and adds new pediatric and Step 5 options.

CHEST's Second Update on VTE: Guidelines for Antithrombotic Therapy
Guideline VTE/Anticoagulation Practice-changing Grade: High

CHEST provides comprehensive updates emphasizing DOAC use for VTE management without cancer.

Finerenone Cuts Heart Failure Events in Preserved Ejection Fraction
Analysis Nephrology / Renal Pharmacy Practice-changing Grade: High

Finerenone reduces cardiovascular events in diabetes with kidney disease.

Finerenone Slows CKD Progression in Type 2 Diabetes
Analysis Nephrology / Renal Pharmacy Practice-changing Grade: High

Finerenone reduces kidney and cardiovascular risks in diabetes patients.

LAAC Noninferior to DOACs in High-Risk Atrial Fibrillation
Analysis Cardiology / Anticoagulation Hypothesis-generating Grade: Moderate

LAAC proves noninferior to DOACs in high-risk AF stroke prevention.

Revised Vancomycin Guidelines by ASHP/IDSA/PIDS/SIDP for MRSA: AUC Monitoring Emphasized
Guideline Vancomycin TDM Practice-changing Grade: High

The latest vancomycin guidelines prioritize AUC-guided monitoring over traditional trough levels for MRSA infections.

Perfusion-Selected Alteplase Extends Thrombolysis Window to 9 Hours
Analysis Neurology / Neuropharmacology Hypothesis-generating Grade: Moderate

Alteplase shows promise for late-presenting stroke when guided by imaging.

ANNEXA-4: Andexanet Reverses Factor Xa Inhibitors Amid Thrombotic Risk
Analysis Cardiology / Anticoagulation Hypothesis-generating Grade: Low

Andexanet alfa reduces factor Xa activity by 92% in bleeding emergencies.

MRI Mismatch Extends Alteplase to Unknown-Onset Stroke
Analysis Neurology / Neuropharmacology Practice-changing Grade: Moderate

MRI-guided thrombolysis may benefit stroke of unknown onset.

2016 ATS/IDSA HAP/VAP Guideline: HCAP Retired, Antibiograms Prioritized
Guideline Hospital-Acquired & Ventilator-Associated Pneumonia Practice-changing Grade: Low

The 2016 ATS/IDSA update reshapes empiric antibiotic selection, de-escalation, and duration of therapy for hospital-acquired and ventilator-associated pneumonia around local resistance data and pharmacokinetic optimization.

Subcutaneous levodopa infusions cut OFF time in advanced Parkinson disease
Analysis Confirmatory Grade: Low

This systematic review of observational data confirms that continuous subcutaneous levodopa infusions reduce motor fluctuations in advanced Parkinson disease, with infusion-site reactions as the dominant tolerability concern pharmacists must proactively manage.

Oral Orforglipron Improves A1c on Basal Insulin Without Hypoglycemia
Analysis Practice-changing Grade: High

ACHIEVE-5 provides the first phase 3 evidence that an oral nonpeptide GLP-1 receptor agonist can be layered onto titrated basal insulin to add glycemic and weight benefit without excess hypoglycemia.