Subcutaneous levodopa infusions cut OFF time in advanced Parkinson disease

This systematic review of observational data confirms that continuous subcutaneous levodopa infusions reduce motor fluctuations in advanced Parkinson disease, with infusion-site reactions as the dominant tolerability concern pharmacists must proactively manage.

📅 Journal publication: Jul 3, 2026 · Last updated: Jul 11, 2026

foslevodopa/foscarbidopaABBV-951VyalevND0612levodopa/carbidopacontinuous subcutaneous infusionParkinson diseasemotor fluctuationsdevice-aided therapysystematic reviewinfusion-site reactions

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Authors: Kiratli Nalbant E, Unlu Acikel S, Ucaryilmaz Ozhamam E, Hayran Y

Citation: Kiratli Nalbant E, Unlu Acikel S, Ucaryilmaz Ozhamam E, et al. A retrospective study of clinical and histopathological characteristics in patients with pityriasis lichenoides: A comparative analysis of pediatric and adult cases. Medicine. 2026;105(27):e49575. doi:10.1097/MD.0000000000049575

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