PharmD Signal

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Clinical Specialty Index

309 articles indexed across 20 specialties, each reviewed by a licensed pharmacist before publication.

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Nephrology / Renal Pharmacy ConfirmatoryGrade: Moderate

Finerenone Outperforms Spironolactone for Cardiorenal Protection in Moderate CKD

Published in: American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions · Jul 20, 2026

Finerenone emerges as the safer choice for CKD patients.

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Neurology / Neuropharmacology ConfirmatoryGrade: Low

Tenecteplase Shortens Stroke Treatment and Transfer Times

Published in: JAMA Network Open · Jul 13, 2026

Tenecteplase speeds up stroke thrombolysis compared to alteplase.

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Rheumatology / Immunology ConfirmatoryGrade: Moderate

EULAR 2025 Streamlines Rheumatoid Arthritis DMARD Management to Nine Recommendations

Published in: Annals of the Rheumatic Diseases · Jun 13, 2026

New EULAR guidelines redefine RA management with DMARDs.

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Showing 9 from 1 topic.Sort: Newest | Oldest
Perioperative Nicotine Withdrawal Amplifies Pain and Opioid Demand
Analysis Pain / Palliative Care Hypothesis-generating Grade: Low
Hu SS, Zhang CF, Lkhagvasuren B, et al.
Sep 10, 2026 · Published in: CNS Neuroscience & Therapeutics

Nicotine withdrawal heightens pain, increasing opioid needs post-surgery.

High-Dose GLP-1 Agonists Safe in Spine Surgery
Analysis Pain / Palliative Care
Stirpe C, Lee B, Lavu M, et al.
Sep 7, 2026 · Published in: The Spine Journal : Official Journal of the North American Spine Society

High-dose GLP-1 therapy is safe for spinal fusion surgery.

Ketamine Beats Lidocaine Early but Not at Six Months
Analysis Pain / Palliative Care Hypothesis-generating Grade: Low
Sucu MG, Yavuz Mollavelioğlu T, Akyüz Yildirim A, et al.
Sep 1, 2026 · Published in: Pain Research & Management

Ketamine offers early pain relief for chronic neuropathic pain.

Intravenous Dexmedetomidine 0.75 mcg/kg May Optimize Analgesia After Femoral Block
Analysis Pain / Palliative Care Hypothesis-generating Grade: Low
Zhai W, Yu Z, Qu Y, et al.
Aug 31, 2026 · Published in: BMJ Open

DEX prolongs analgesia in ACL reconstruction at safer doses.

Methadone Beats Buprenorphine-Naloxone for 1-Year Survival After Overdose
Analysis Pain / Palliative Care Hypothesis-generating Grade: Low
Kleinman RA, Larney S, Sule NO, et al.
Aug 25, 2026 · Published in: JAMA Network Open

Methadone shows improved survival in opioid overdose survivors.

Psychosocial Complexity Does Not Predict Withdrawal During Methadone-Buprenorphine Transfer
Analysis Pain / Palliative Care Hypothesis-generating Grade: Low
Tremonti C, Mills L, Lintzeris N, et al.
Jul 23, 2026 · Published in: Drug and Alcohol Review

Withdrawal during methadone-to-buprenorphine transfers peaks and is predictable.

Buprenorphine-Naloxone Cuts Nonfatal Overdose vs XR Naltrexone Post-Withdrawal
Analysis Pain / Palliative Care Confirmatory Grade: Moderate
Hsu HE, Lodi S, Yan S, et al.
Jul 14, 2026 · Published in: JAMA Network Open

Buprenorphine-naloxone reduces overdose risk more effectively than XR naltrexone.

North Carolina Pharmacists Ambivalent but Willing on Methadone Dispensing
Analysis Pain / Palliative Care Hypothesis-generating Grade: Low
Carpenter DM, Shubel C, Marley GT, et al.
Jul 13, 2026 · Published in: Journal of Addiction Medicine

Pharmacists willing but cautious with methadone services for OUD.

Updated PROSPECT Guidance Reshapes Post-Caesarean Analgesia Regimens
Analysis Pain / Palliative Care Confirmatory Grade: Moderate
Crowe G, Atterton B, Roofthooft E, et al.
Jun 15, 2026 · Published in: Anaesthesia

Optimizing pain relief post-caesarean ensures faster, safer recovery.