Hybrid Closed-Loop Systems Improve Pediatric Diabetes Management

Sep 30, 2026 · Published in: Pediatric Diabetes

📅 Journal publication: 2026 (online Aug 12, 2026) · Last updated: Oct 7, 2026

Background Information

Hybrid closed-loop systems enhance pediatric diabetes control safely.

Managing glycemic control in young children with Type 1 diabetes is challenging, and hybrid closed-loop systems could offer better control and safety. The system increased time in range by 9.95% and reduced glycated hemoglobin by 0.51% without significant risk of severe hypoglycemia or diabetic ketoacidosis. While the hybrid closed-loop system shows promise, further large-scale studies are necessary to confirm long-term safety and efficacy. Hybrid closed-loop systems improve glycemic control in young children with Type 1 diabetes without added risk of adverse events.

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Authors: Zhang T, Wang N, Wang B, Wang M, Zhang J

Citation: Zhang T, Wang N, Wang B, et al. Efficacy and safety of hybrid closed-loop systems in children aged < 7 years with type 1 diabetes: a systematic review and meta-analysis of randomized controlled trials. Pediatric diabetes. 2026;2026:e006. doi:10.48130/pedi-0026-0006

Article Links: PubMed · Journal / DOI · Free Full Text (PMC)

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