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Pharmacist-Embedded Liver Fibrosis Screening Finds Hidden Cirrhosis in Diabetes

MASLDtype 2 diabetesliver fibrosisFIB-4vibration-controlled transient elastographyVCTEFibroScanambulatory care pharmacistcollaborative care agreementfeasibility studysafety netresmetiromGLP-1 receptor agonistmanaged care pharmacy Clinical Pharmacy Practice

Background Information

Pharmacists enhance liver disease detection in diabetes care.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in type 2 diabetes mellitus (T2DM) but often undiagnosed. Integrating risk stratification in pharmacy care could enhance detection. Post-intervention, 87% of patients with elevated Fibrosis-4 index (FIB-4) scores were referred for vibration-controlled transient elastography (VCTE), with 85% completing it. This led to the identification of eight new cases of fibrosis. The study shows that pharmacists can effectively integrate MASLD risk assessment into diabetic care workflows, improving referral rates and fibrosis detection. However, this was a feasibility pilot study and further research is needed to assess scalability. Pharmacist integration in diabetes management improves liver fibrosis detection in primary care.

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Authors: Wexler RP, Chimene-Weiss J, Cameron C, Schipelliti S, Vuddanda P, Roman A, Mohanty A

Citation: Wexler RP, Chimene-Weiss J, Cameron C, et al. Embedding metabolic dysfunction-associated steatotic liver disease fibrosis risk stratification within pharmacist-integrated diabetes comanagement in primary care. Journal of managed care & specialty pharmacy. 2026;32(10):1289-1295. doi:10.18553/jmcp.2026.32.10.1289

Article Links: PubMed · Journal / DOI · Free Full Text (PMC)

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