Pharmacist Penicillin Allergy Interview Delabels Without Skin Testing
This small retrospective cohort shows that a structured pharmacist-led interview alone can modify inaccurate penicillin allergy labels when skin testing and oral challenge are not feasible.
📅 Journal publication: Mar 2026(online Mar 16, 2026)·Last updated: Oct 13, 2026
Penicillin allergies are often inaccurately documented, leading to inappropriate antibiotic use. This study explores a pharmacist-led method to improve allergy documentation. In the study, 17.1% (6 of 35) of participants had their allergy profile modified compared to none in the control group, showing statistically significant improvement (P < .03). The Allergy to β-Lactam Evaluation (ABLE) process demonstrates potential for enhancing allergy documentation accuracy, despite its small sample size, which may limit generalizability. Pharmacist-led interviews using the ABLE process can improve penicillin allergy documentation.
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Citation:Puckett JC, Powers C, Shin M, et al. Implementation of a Pharmacist-Led Penicillin Allergy Interview at a Veterans Care Facility. Federal practitioner : for the health care professionals of the VA, DoD, and PHS. 2026;43(3):106-109. doi:10.12788/fp.0684
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Executive Summary
Study Design
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