Deintensification Lags Despite Overtreatment in Older Diabetes Patients
This cohort study quantifies how often older adults with type 2 diabetes have their glucose-lowering regimens intensified or scaled back based on health status and glycemic control, highlighting persistent overtreatment.
type 2 diabetesolder adultsdeprescribingdeintensificationsulfonylureasinsulinHbA1chypoglycemiacohort studygeriatric pharmacyovertreatmentEndocrinology / Diabetes / Obesity
Background Information
Exploring medication changes for older adults with diabetes.
Understanding medication changes in older adults can improve outcomes and reduce adverse effects. No abstract available; key results cannot be determined. The study appears to explore diabetes medication management, not opioid stewardship. Study lacks accessible details due to missing abstract.
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Authors:Le P, Guo N, Misra-Hebert AD, Casacchia NJ, Yue Y, Gasoyan H, Taksler GB, Rothberg MB
Citation:Le P, Guo N, Misra-Hebert AD, et al. Intensification and Deintensification of Diabetes Medications Among Older Adults With Type 2 Diabetes. JAMA internal medicine. 2026. doi:10.1001/jamainternmed.2026.3483
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Executive Summary
Study Design
Patient Population
Primary Outcomes
Secondary Outcomes & Safety Profile
Pharmacist Implications
Clinical Pearls
Limitations
Controversies & Evidence Gaps
Cost & Logistics
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