Tirzepatide in UK Digital Practice: Real-World Weight Loss at Scale

This very large self-pay digital cohort shows tirzepatide weight loss approximating trial efficacy in routine use, while highlighting treatment continuity, not maximal dose, as the key driver for obesity pharmacists.

📅 Journal publication: Oct 2026 (online Aug 6, 2026) · Last updated: Sep 26, 2026

tirzepatideMounjaroGLP-1 receptor agonistGIPobesityweight lossreal-world evidencedigital healthretrospective cohortUKadherencedose titration Endocrinology / Diabetes / Obesity

Background Information

Digital prescribing supports significant weight loss with tirzepatide.

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Authors: Rosenior-Patten O, Lees Z, Rowe R, Hussain S, Ahmad E, Brooke E, Dix S, Maybury C

Citation: Rosenior-Patten O, Lees Z, Rowe R, et al. Real-World Effectiveness and Treatment Patterns of Tirzepatide in a Large UK Digital Health Cohort. Diabetes, obesity & metabolism. 2026;28(10):9621-9632. doi:10.1111/dom.71067

Article Links: PubMed · Journal / DOI · Free Full Text (PMC)

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