Pharmacist anti-MRSA time-outs cut use mainly in emergency departments
This interrupted time-series shows a pharmacist-led 72-hour anti-MRSA reassessment reduces vancomycin days of therapy and therapeutic drug monitoring burden in high-acceptance areas, offering a resource-conscious targeting strategy for stewardship programs.
Targeted pharmacist-led interventions reduce intensive care antibiotic use.
Targeted antimicrobial stewardship can optimize antibiotic use and resource allocation, especially in resource-limited settings. Antibiotic days of therapy decreased significantly in emergency medicine and critical care, with high acceptance rates; therapeutic drug monitoring tests also decreased. Pharmacist-led interventions are effective in specific departments, emphasizing the importance of strategic targeting for optimal outcomes without impacting stay duration or mortality. Focused antimicrobial time-outs effectively reduce unnecessary antibiotic use in key hospital areas.
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Authors:Yamamoto R, Tagashira Y, An DD, Enatsu Y, Satake M, Aiso Y, Gu Y
Citation:Yamamoto R, Tagashira Y, An DD, et al. Where antibiotic time-outs work: department- and ward-stratified effects of a pharmacist-led anti-MRSA time-out. Antimicrobial stewardship & healthcare epidemiology : ASHE. 2026;6(1):e208. doi:10.1017/ash.2026.10778