Carbapenem stewardship in surgical wards could curb rising resistance.
High carbapenem use in surgical wards drives antimicrobial resistance, requiring strategic interventions to optimize antibiotic stewardship. The study aims to measure changes in carbapenem use and resistance patterns due to a multimodal intervention across surgical wards. This study provides prospective data supporting multimodal stewardship interventions, addressing a gap typically filled by retrospective studies or single-component programs. Multimodal stewardship interventions may reduce carbapenem use and resistance in surgical wards, enhancing patient safety.
Authors: Vazquez-Piqueras N, Padullés A, Sabé N, Shaw E, Abelenda-Alonso G, Suárez-Lledó A, Costa RM, Peláez N, Molina Molina GJ, Dordal MT, Andres B, Jiménez-Martínez E, Laguna MDM, Peñafiel J, Carratalà J, Oriol I
Citation: Vazquez-Piqueras N, Padullés A, Sabé N, et al. Effect of a multimodal intervention in general and digestive surgery wards on carbapenem use and antimicrobial resistance: protocol for a prospective, quasi-experimental interrupted time-series study. BMJ open. 2026;16(6):e118013. doi:10.1136/bmjopen-2026-118013
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