Sepsis survivors carry elevated psychiatric risk for five years
This nationwide Swedish cohort quantifies the long-term burden of new mood and anxiety morbidity after ICU-treated sepsis, reinforcing the pharmacist's role in post-sepsis psychotropic stewardship and mental health screening.
Sepsis survivors face an increased risk of developing psychiatric disorders.
Understanding the link between sepsis and subsequent psychiatric morbidity can improve post-ICU care and support strategies. Sepsis patients showed a higher risk of psychiatric events compared to controls, especially within the first year, with attenuated but elevated risk up to five years. Highlighting the need for psychiatric monitoring in sepsis survivors; however, the study relies on registry data and may not capture all potential confounders. Sepsis significantly increases the risk of psychiatric disorders, particularly within the first year post-ICU.
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Authors:Wetterberg H, Nilsson A, Linder A, Lengquist M, Frigyesi A, Sundén-Cullberg J, Inghammar M
Citation:Wetterberg H, Nilsson A, Linder A, et al. Sepsis and Subsequent Psychiatric Morbidity: A Nationwide Population-Based Matched Cohort Study, 2008-2019. Critical care medicine. 2026;54(7):1527-1533. doi:10.1097/CCM.0000000000007105