Practical Framework for Managing Anticoagulant-Associated Bleeding
A contemporary narrative review consolidating bleeding risk stratification, severity assessment, reversal strategy, and anticoagulation resumption for cardiology and anticoagulation pharmacists.
📅 Journal publication: Jul 8, 2026·Last updated: Aug 23, 2026
Bleeding risks complicate anticoagulant therapy management in cardiovascular patients.
Managing bleeding in patients on anticoagulant therapy is crucial due to its high association with morbidity and mortality. The article provides patient-centered flowcharts for acute bleeding management and safe anticoagulation resumption. Highlights the need for individualized anticoagulant regimens and access to reversal agents; emphasizes risk versus benefit balance. Balancing thrombotic and bleeding risks is essential in anticoagulant therapy management.
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Authors:Galli M, Simeone B, Ten Berg J, Capodanno D, Valgimigli M, Sciarretta S, Greco E, Kastrati A, Montalescot G, Gibson CM, Gorog DA, Mehran R, Angiolillo DJ
Citation:Galli M, Simeone B, Ten Berg J, et al. Managing bleeds on anticoagulant therapy: a practical guide for clinicians. European heart journal. Acute cardiovascular care. 2026;15(7):557-572. doi:10.1093/ehjacc/zuag035